Biomedical and Biotechnology Research Journal (BBRJ)

REVIEW ARTICLE
Year
: 2021  |  Volume : 5  |  Issue : 4  |  Page : 374--379

Co-regulatory network of transcription factor and microrna: A key player of gene regulation


Akshara Pande 
 School of Computing, Graphic Era Hill University, Dehradun, Uttarakhand, India

Correspondence Address:
Akshara Pande
School of Computing, Graphic Era Hill University, Dehradun, Uttarakhand
India

Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA at posttranscriptional level by affecting the transcription and translation. Furthermore, sometimes, both miRNAs and TFs regulate one another's expressions; as a consequence, this may influence the expression of the target gene. In order to understand the main co-regulatory mechanisms underlying, it is important to identify biologically relevant network motifs involving TFs, miRNAs and their targets. The present study focuses on TF, miRNA and target gene interactions.


How to cite this article:
Pande A. Co-regulatory network of transcription factor and microrna: A key player of gene regulation.Biomed Biotechnol Res J 2021;5:374-379


How to cite this URL:
Pande A. Co-regulatory network of transcription factor and microrna: A key player of gene regulation. Biomed Biotechnol Res J [serial online] 2021 [cited 2022 Jan 20 ];5:374-379
Available from: https://www.bmbtrj.org/article.asp?issn=2588-9834;year=2021;volume=5;issue=4;spage=374;epage=379;aulast=Pande;type=0