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ORIGINAL ARTICLE
Year : 2022  |  Volume : 6  |  Issue : 3  |  Page : 454-457

Seroprevalence of hepatitis B viral infection in the okpoko community


1 Department of Microbiology, Abia State University, Uturu, Abia
2 Department of Food Science and Technology, Abia State University, Uturu, Abia
3 Department of Medical Laboratory Sciences, Nnamdi Azikiwe University, Awka, Anambra, Nigeria

Correspondence Address:
Ndubuisi Obiora Nwachukwu
Department of Microbiology, Abia State University, P. M. B 2000, Uturu, Abia
Abia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bbrj.bbrj_85_22

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Background: Hepatitis B virus infection (HBV) is a potentially life-threatening liver infection. Little is known about seroprevalence at the community level. A cross-sectional, community-based study was conducted at Okopko, an urban slum in Ogbaru Local Government Area of Anambra State, Nigeria, using a multistage sampling technique. Stages were the constituency level, ward, and household levels. A total of 867 participants were enrolled. Methods: Testing for the markers of HBV was performed using Diagnostic Kit (USA). The test panel detects hepatitis B surface antigen (HBsAg), hepatitis e antigen (HBeAg), antibody to e antigen (HBeAb), core antibody (HBcAb), and surface antibody (HBsAb) using colloidal gold and membrane chromatographic technology. Results: The seroprevalence of HBsAg was 6.6%. Seroprevalence was higher in males (7.4%) than in females (5.5%) (P > 0.05). The peak seroprevalence occurred in the age group of 40–49 years for both males (13.6%) and females (8.1%) (P < 0.05). Exactly 4.7% were positive for HBeAg and 5.8% for HBsAg + HBeAg + HBcAb. Only 1% was positive for HBsAb. Conclusion: Okpoko community has a high intermediate prevalence rate of HBV infection. The HBV vaccination level is very low in the community.


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