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CASE REPORT
Year : 2022  |  Volume : 6  |  Issue : 1  |  Page : 156-158

S-100 negative cutaneous granular cell tumor: A rare case presentation


1 Department of Pathology, Medical College and Hospital, Kolkata, West Bengal, India
2 Department of Pathology, Rampurhat Government Medical College and Hospital, Rampurhat, West Bengal, India

Correspondence Address:
Arup Mishra
Department of Pathology, Medical College and Hospital Kolkata, 88, College Street, Kolkata - 700 073, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bbrj.bbrj_230_21

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Cutaneous granular cell tumor (GCT) is an uncommon benign mesenchymal neoplasm of skin constitutes 0.5% of all soft-tissue tumors, presenting as slowly growing papule or nodule. Familial cases and congenital GCT have been reported to be associated with multiple lesions. Classic GCT is usually S-100 and CD 68 positive. Here, we report the case of a 16-year-old male patient presented with a 2-year history of slowly growing firm, nontender, nodular masses all over the body without any lymphadenopathy. Hematoxylin and eosin-stained sections show histological picture of GCT, but it is CD-68 positive and S-100 negative on immunohistochemistry. Due to its rare immunohistological feature, we are presenting this case. Documentation and reporting of such aberrant cases are necessary for further study on actual origin of these tumors which may aid for better management in future.


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