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Year : 2017  |  Volume : 1  |  Issue : 1  |  Page : 1-8

Liposomes as potential nanocarriers for theranostic applications in chronic inflammatory lung diseases

1 Koc University Research Center for Translational Medicine (KUTTAM), Graduate School of Health Sciences, Koc University, Istanbul, Turkey
2 Koc University Research Center for Translational Medicine, School of Medicine, Koc University, Istanbul, Turkey

Correspondence Address:
Hasan Bayram
Koc University Research Centre for Translational Medicine (KUTTAM), Koc University, Istanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/bbrj.bbrj_54_17

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Chronic obstructive pulmonary disease and asthma affect millions of people worldwide. Conventional treatments are not sufficient at preventing the progression of these diseases. The treatments are unspecific, and when administered systematically, and in high doses, they have adverse health effects. Further, the current diagnostic methods are poor and they are not capable of identifying the accurate state of the disease. Nanoparticle-based theranostics (NBTs) are well-established systems that simultaneously provide treatment and diagnostics. Various nanocarriers can be used in NBT and are designed according to the need. In this review, liposome-based theranostic systems are evaluated and possible modifications that could provide better drug delivery and accumulation and diagnosis are exemplified. These systems can be applied to conventional therapeutics to avoid side effects and perhaps overcome the challenges that interfere with their cellular accumulation.

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